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ChatGPT’s explanation of “estrangement”: “Estrangement” refers to the sense of distance or obstacles between people due to some reason. It is usually used to describe the lack of smooth communication in emotions, thoughts, or communication.
For example:

The distance between them makes communication difficult.
The existence of barriers makes the relationship between friends become distant.

The origins of the word "estrangement" can be traced back to ancient Chinese texts, and are often used to describe barriers or isolation in interpersonal relationships.

ChatGPT definition